Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.Decylubiquinone (DUb), a coenzyme Q10 analog, was reported to inhibit breast cancer growth and metastasis by us.However, the influence of DUb on CRC remains unclear.Herein, we found that DUb significantly inhibited CRC growth in the patient-derived xenograft (PDX
Amorphous solid dispersions (ASDs) enable formulations to improve the solubility of poorly soluble active pharmaceutical ingredients (APIs).The amorphous Human Hair Blend Lace Frontal Wig state is reached through the disruption of the crystalline lattice of an API resulting in an increased apparent solubility with faster disintegration.Nevertheless
Abstract Objectives Shiga toxin-producing Escherichia coli strains LAA-positive are important cause of human infection.The capability to adhere to epithelial cells is a key virulence trait, and genes codified in LAA pathogenicity island Bow could be involved in the adhesion during the pathogenesis of LAA-positive STEC strains.Thus, our objectives w